2003-10-23 09:49:10 UTC
riduca il testosterone nel sangue in soggetti sani. Accuratamente da evitare
se si hanno a cuore la propria libido e la performance sportiva.
J Steroid Biochem. 1983 Mar;18(3):369-70.
Decrease of serum total and free testosterone during a low-fat high-fibre
Hamalainen EK, Adlercreutz H, Puska P, Pietinen P.
The concentrations of serum total and free testosterone were studied in 30
healthy, middle-aged men during a dietary intervention program. When men
were transferred from their customary diet to an experimental diet, which
contained less fat with a higher polyunsaturated/saturated ratio (P/S-ratio)
and more fibre, there was a significant decrease in serum total testosterone
concentrations (22.7 +/- 1.2 vs 19.3 +/- 1.1 nmol/l SEM, P less than 0.001).
Furthermore, serum free, unbound testosterone fell from 0.23 +/- 0.01 to
0.20 +/- 0.01 nmol/l SEM (P less than 0.01). The hormonal changes were
reversible. This observation suggests that testosterone activity in plasma
can at least partly be modified by changing the composition of the diet.
Am J Clin Nutr. 1996 Dec;64(6):850-5.
Effects of dietary fat and fiber on plasma and urine androgens and estrogens
in men: a controlled feeding study.
Dorgan JF, Judd JT, Longcope C, Brown C, Schatzkin A, Clevidence BA,
Campbell WS, Nair PP, Franz C, Kahle L, Taylor PR.
Division of Cancer Prevention and Control, National Cancer Institute,
Bethesda, MD 20892-7326, USA. ***@dcpcepn.nci.nih.gov
We conducted a controlled feeding study to evaluate the effects of fat and
fiber consumption on plasma and urine sex hormones in men. The study had a
crossover design and included 43 healthy men aged 19-56 y. Men were
initially randomly assigned to either a low-fat, high-fiber or high-fat,
low-fiber diet for 10 wk and after a 2-wk washout period crossed over to the
other diet. The energy content of diets was varied to maintain constant body
weight but averaged approximately 13.3 MJ (3170 kcal)/d on both diets. The
low-fat diet provided 18.8% of energy from fat with a ratio of
polyunsaturated to saturated fat (P:S) of 1.3, whereas the high-fat diet
provided 41.0% of energy from fat with a P:S of 0.6. Total dietary fiber
consumption from the low- and high-fat diets averaged 4.6 and 2.0
g.MJ-1.d-1, respectively. Mean plasma concentrations of total and
sex-hormone-binding-globulin (SHBG)-bound testosterone were 13% and 15%
higher, respectively, on the high-fat, low-fiber diet and the difference
from the low-fat, high-fiber diet was significant for the SHBG-bound
fraction (P = 0.04). Men's daily urinary excretion of testosterone also was
13% higher with the high-fat, low-fiber diet than with the low-fat,
high-fiber diet (P = 0.01). Conversely, their urinary excretion of estradiol
and estrone and their 2-hydroxy metabolites were 12-28% lower with the
high-fat, low-fiber diet (P < or = 0.01). Results of this study suggest that
diet may alter endogenous sex hormone metabolism in men.
Inviato via http://arianna.libero.it/usenet/